Greg Giraldo was married twice. He married first at the age of 23, but that union ended in divorce two years later. Giraldo then married MaryAnn McAlpin in 1999, and though the couple were estranged at several points throughout their relationship, they would stay married until the day Giraldo died, as his biography on Celebrity Net Worth explains. 

After concerned friends, colleagues, and family alerted the authorities that Giraldo had failed to make two scheduled appearances on the same day, police were asked to perform a welfare check on the star in his New Brunswick, New Jersey hotel room. Finding Giraldo unresponsive though still alive, the comedian was then transported to a nearby hospital, where he remained in a coma on life support for five days. After nearly a week, Giraldo's family decided to remove Giraldo from life support, at which point he died, according to TMZ.

Among Giraldo's most successful projects, perhaps, was a 2009 CD and DVD comedy release called "Midlife Vices" (via IMDb). In it, Giraldo spoke openly of his long history of issues with drug and alcohol use, which were worsened by the temptations of show business, based on reporting from Vulture. Though Giraldo managed sobriety on several occasions before his death, fellow comedian Jim Norton told Vulture, "In the last three years or so, it became more and more apparent that he was struggling. I would say to him, 'hey man, did you relapse?"

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